Insertion and Deletion Processes in Recent Human History

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Insertion and Deletion Processes in Recent Human History

BACKGROUND Although insertions and deletions (indels) account for a sizable portion of genetic changes within and among species, they have received little attention because they are difficult to type, are alignment dependent and their underlying mutational process is poorly understood. A fundamental question in this respect is whether insertions and deletions are governed by similar or differen...

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1 FB Biologie und Informatik, Goethe-Universität, 60054 Frankfurt am Main, Germany, [email protected] 2 Department of Mathematics, University of Idaho, P.O. Box 441103. Moscow, ID 83844-1103, USA, [email protected] 3 FB Mathematik, Goethe-Universität, 60054 Frankfurt am Main, Germany, [email protected] 4 Bioinformatik, Heinrich-Heine-Universität, 40225 Düsseldor...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2010

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0008650